Sentence examples for marker of transformation from inspiring English sources

These findings indicate that GST is of limited use as a marker of transformation in the human cervix uteri.

NCAM1 has previously been identified as being a marker for cancer-propagating WT cells [ 47], suggesting its potential as a marker of transformation from NRs.

The first description of the protein that would eventually come to be known as osteopontin (OPN) was as a marker of transformation of epithelial cells (Senger et al, 1979).

Given that KI/KI h-Ras lines were refractory to this effect (Fig 4B), +/+ Vec, KI/KI vec, and KI/KI h-Ras lines were assayed their ability to form colonies in soft agar, a known marker of transformation.

The destination vector dpGreenmCherry contains a plasma membrane-localized mCherry coding sequence driven by the 35S promoter and is used as a selectable marker of transformation at the mature seed stage (Duan et al., 2013).

Integrin phenotyping disclosed that alpha 3/beta 1 expression is associated with tumour progression, alpha v/beta 3 is a marker of transformation, alpha 4 is rarely expressed and alpha 5 is expressed by about 50% and 30% of the primary and metastatic lesions respectively.

In general, all sublines exhibited increase markers of transformation.

Cell model systems have been used to identify molecular markers of transformation during prostate cancer development.

The results obtained from tumour extracts, cell models and models of implanted xenografts demonstrate the potential of MRS in assessing surrogate markers of transformation and response to therapy.

Molecular profiles were constructed based on the selected cell line's ability to express various markers of transformation (c-Neu, cyclinD1, p21, p27 waf)), cell status (VEGF, IGF-R, c-Met, CK19), invasiveness (MMPs -12 and -13) and inflammation (NFκB).

Thus, transcripts exhibiting highly significant over expression in all classes of abnormal astrocytes, including trisomic BG01V APCs, CCF-STTG1 astrocytoma cells and glioblastoma patient samples with respect to diploid H9 APCs (Table 1, GND > C) may be diagnostic markers of transformation and/or potential therapeutic targets (i.e. changes in gene expression that are consequences of transformation).