Your English writing platform
Discover LudwigExact(7)
We evaluated the performance of QF-TB-IT as a marker of TB infection, defined as LTBI children with a known family TB contact (32 children) and active TB children (32 children) versus healthy contacts (12 children) or children with LTBI and no TB contact (22 children).
The properties of QF-TB-IT as a diagnostic marker of TB infection were assessed using the area under the receiver operating characteristics ROC curve (AUC), and estimates of sensitivity and specificity when data were dichotomized at the usual positivity threshold.
IP-10 has been suggested as a marker of TB treatment efficacy – serial samples show reductions in levels at 2 months in cured TB patients, with no reduction in non-responders [15].
A positive TST response is a marker of TB exposure and also increases the likelihood of occurrence of TB in a child with suspected pulmonary tuberculosis.
However, the TST is an imperfect marker of TB infection and previous reports indicate that 10 25% of persons with active TB disease have a negative TST result [ 1, 4, 5].
To determine whether clusterin has a role as a marker of TB or indicates more general response to antigen stimulation, we are currently attempting to find clear and simple methods in detecting these alterations for mass screening.
Similar(53)
We also evaluated the relationship between SFC counts and markers of TB disease severity at baseline.
Critical to the success of identifying relevant markers of TB is access to clinical samples from diverse, longitudinal studies in human cohorts.
The majority of the RIF resistant isolates and clinical samples in this study were also MDR-TB suggesting that RIF resistance may not only be a suitable surrogate marker of MDR-TB in high TB incidence settings as suggested by the WHO but in medium TB incidence settings like South Korea as well.
Since most (92.1%) of RIF resistant strains in this study were also resistant to INH, the results suggest that RIF resistance may also be a suitable surrogate marker of MDR-TB in a setting of moderate TB incidence such as Korea.
However, the development of a prognostic marker for TB would allow treatment of the small fraction of latently infected individuals in high endemic regions most at risk of developing contagious TB.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com