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The RBC membrane Na+/K+-ATPase measurements appears to be an sensitive marker of subtle cerebral deterioration.
According to these data, cystatin C appeared to be an accurate marker of subtle changes in GFR.
Our findings suggest that in some circumstances swing time variability may be a more sensitive marker of subtle underlying changes in neural control and in the locomotor system's ability to repeatedly and precisely generate and execute neural commands.
However, neurological score accounts for only 3% of the variance in S100β, and on the basis of this evidence it can not be recommended as a surrogate marker of subtle neurological outcomes after CABG surgery.
Cystatin C is an accurate marker of subtle changes in GFR, and it may be superior to creatinine when assessing this parameter in clinical practice in critically ill patients.
This highlights the limitation of relying on the presence of microbleeds as a marker of subtle white matter damage and demonstrates that significant white matter abnormality may be present following traumatic brain injury even when gradient-echo MRI is normal.
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Unsophisticated measures such as reported right-handedness, left-handedness and mixed-handedness, as used in the Finnish study, 6 are imprecise markers of subtle developmental deficits and may therefore be of limited use in research.
54 55 Furthermore, the presence of thyroid autoantibodies might be a marker of underlying subtle alteration in thyroid reserve.
Furthermore, NF is suggested as a triage-like marker for subtle parieto occipital dysfunction that may also occur in early stages of Alzheimer's disease (with some reported aggressivity), possibly also early in HIV infection.
This could be due to the insensitivity of these markers to subtle cardiac injury caused by PM under variable background of the host species.
Local TSPO overexpression in response to damage makes it a potentially ideal and sensitive marker for the detection of subtle changes in the region of brain insult (Fig. 5).
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Justyna Jupowicz-Kozak
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