Demonstrating antiatherothrombotic properties of dipeptidyl peptidase-4 inhibitors on proven markers is of substantial clinical significance.
Although EGFP-LC3 is a marker of autophagosomes, a substantial fraction of the protein is often present in the nucleus as well [17], [18], [19], [20], [22].
It therefore appears necessary to draw a clear distinction between the validity of plasma osmolality as a marker of acute and substantial body water loss, and its usefulness in differentiating between the LD and HD in less extreme environments.
The resultant annotated EST markers will then be of substantial value for marker-assisted introgression programs based on interspecific crosses using wild Cicer species that harbour agronomically valuable genes.
However, the effects are mild in degree compared with previous studies (e.g., Hayman et al. 2003), and it does not seem that firing rate is a substantial marker of global spatial location, though it may provide a modulating influence.
Patient 10 was omitted because of substantial independent bone marker migrations (ME > 0.2 mm).
Speech-evoked auditory brainstem responses (speech-ABR) provide a reliable marker of learning disability in a substantial subgroup of individuals with language-based learning problems (LDs).
In silico comparative mapping of physically mapped ILP markers demonstrated substantial percentage of sequence-based orthology and syntenic relationship between foxtail millet chromosomes and sorghum (∼50%), maize (∼46%), rice (∼21%) and Brachypodium (∼21%) chromosomes.
Furthermore, the broad representation of DIMM among most of peptide markers here surveyed (only two or three of 24 markers lacked substantial DIMM expression) suggests the percentage of identifiable DIMM cells will increase as markers for other Drosophila peptide systems become available.
The concept of titrating chronic HF therapies using physiologic markers, so called "biomarker guided therapy (BGT)", has become an area of substantial interest in HF given the underutilization of evidence-based medications and suboptimal outcomes with current management strategies.
