Sentence examples for marker of stem from inspiring English sources

It has become a high priority to find a molecule (preferably one functionally involved in determining stemness) that is a specific marker of stem cell function, for their evaluation during normal and pathogenic development.

It is further revealed by gene expression analysis that cells proliferated in the EGF-incorporating collagen hydrogel contained subpopulations expressing the marker of stem cells, neurons, astrocytes, or oligodendrocytes.

These data together with other data presented below, lead us to conclude that CD133 is probably not a specific marker of stem cells in CRC.

Interestingly, in separate experiments, we show that GTR1 EBs treated for 24 hours with HBR concomitantly expressed consistent amounts of both Smad4 and α-sarcomeric actinin, a marker of stem cell commitment to the cardiac lineage (Figure 6B).

Predictably, nestin, a marker of stem cells, was increased in the fetal samples; vimentin was consistently expressed in all samples (Figure 5C) while glial fibrillary acidic protein-encoding tags were minimally detected.

Although its biological function remains unknown, it also serves as a marker of stem cells in a variety of non-hematopoietic tissues, including neural and glial cells in the fetal brain as well as prostatic epithelia, muscle, kidney, liver and corneal stroma, and some cancerous tissues [15] [24].

Recently, ALDH1 activity has been employed as a marker of stem-like cells in many cancers, such as cervical and breast cancer [ 22].

In tumourigenicity assays, CD44 was previously identified as a marker of stem-like TIC in colon cancer using 15 clinical samples (Chu et al, 2009).

However, the expression pattern of MSC-related antigens cannot be used as a specific marker of stem-like cells in osteosarcoma, since parental MNNG/HOS cells exhibited an immunophenotype similar to that of sarcospheres.

The VENICE study will also collect data on levels of CD34+ cells in the blood, as this may have predictive value as a marker of stem-cell reserves and regenerative capability [ 41- 43].

In a large cohort of women with locally advanced breast cancer treated with NAC, we have shown that expression of ALDH1, a marker of stem-like cancer cells, strongly predicts for innate resistance to sequential FEC/TAX chemotherapy.