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It is clear that in addition to being a well-documented marker of solid human tumour tissue, hypoxia also acts on several levels to promote further tumour development.
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The passage rate of the marker of the solid particles in buffalo rumen, at variance with the structural carbohydrates of the diet, is more variable compared with that of the sheep.
The passage rate of the marker of the solid particles, through the first compartment, k1 (2.86% h− 1 and 2.54% h− 1 for the buffalo and the sheep) and through the entire intestinal tract, MRT (57.50 and 58.88 h for the buffalo and the sheep) does not show significant differences in the two species.
An overview of the application of markers for solid tumours is presented.
The measurement of oestrogen receptor (ER) status is one of a very small number of molecular markers for solid tumours that have a large impact both on estimation of prognosis and the choice of therapy for the individual patient.
These objectives remain elusive mainly due to the lack of specific genetic markers for solid tumours.
Ki-67 has been used as a marker for cell proliferation of solid tumors and some hematological malignancies.
In addition, IAP overexpression is a poor prognostic marker for a variety of solid tumors and hematological malignancies [ 15].
In recent years ALDH has been recognised as a CSC marker in a number of solid tumours.
In this regard, it has been shown that IAP overexpression is a poor prognostic marker for a variety of solid tumors and hematological malignancies [ 23].
DOI: 10.1038/sj/bjc/6600075 www.bjcancer.com © 2002 The Cancer Research Campaign Vascular endothelial growth factor (VEGF) is one of the strongest promoters of angiogenesis, and it has been indicated, that the preoperative serum VEGF concentration is a prognostic marker in a variety of solid tumours (Salven et al, 1999a; Chin et al, 2000).
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