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Par j 2 Lipid Transfer Protein is one of the most important allergens in southern Europe and a well-established marker of sensitization in Parietaria pollen allergy.
We measured SSEP amplitudes as a marker of sensitization, and SSEP habituation over two sequential blocks during uninterrupted peripheral stimulation in a well-characterized group of 60 MOH patients who underwent GRIA3 rs3761555 polymorphism analysis.
This potential underlying mechanism supports our results, assuming that pain hypersensitivity is a marker of sensitization of the nervous system.
We chose total IgE as a marker of general IgE synthesis, and IgE specific to grass (Phleum pretense) as an important marker of sensitization, because grass pollen is ubiquitous and has previously been demonstrated to be the most common allergen in other North Atlantic environments (Clausen et al. 2008; Krause et al. 2002b).
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For instance, the NHS Plus review of latex allergy 4 reported three studies showing that changing from powdered to powder-free latex gloves was associated with significant reduction in symptoms, disease-severity indicators and immunological markers of sensitization.
The cross-sectional nature of this sample prohibited us from distinguishing between which DNA-M variations at CpG sites may have caused, been caused by, or just been markers of sensitization.
When using IgE levels as a marker of food sensitization, we found that serum PFNA was inversely associated with food sensitization (NHANES 2005 2006).
Animal studies [31] have also shown that depression may induce hyperalgesia, another marker of central sensitization.
As a marker of central sensitization, allodynia has been proposed as a risk factor for progression to chronic migraine [6].
The purpose of this study was to correlate tear serotonin levels, as a marker of nociceptor sensitization, to facets of dry eye (DE), including symptoms and signs.
The lowered pain threshold results in hyperalgesia and allodynia, which is the clinical marker of central sensitization of the trigeminal nucleus caudalis in migraine.
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