Sentence examples for marker of sensitivity from inspiring English sources

Since the discovery of sensitizing EGFR mutations as a predictive marker of sensitivity to EGFR tyrosine kinase inhibitors (TKIs), the field of targeted therapy in non-small cell lung cancer (NSCLC) has been revolutionized.

TS may be a suitable marker of sensitivity to pemetrexed-based chemotherapy in patients with NSCLC.

However, no reliable molecular marker of sensitivity, resistance, or toxicity to 5-FU has been validated until now[ 10].

Moreover, our data suggest that p57Kip2 could be used as a marker of sensitivity to the cell-cycle inhibitor seliciclib.

Locomotor stimulation in response to alcohol also is used in animal studies as a marker of sensitivity.

We did not use clinical parameters other than duration of hospitalisation, as a marker of sensitivity of the questionnaire in detecting severity of illness.

For the increasing number of developmentalists turning to research on genetic and biological markers of sensitivity, this article serves to inform the biological role of the prominently studied genes in human development.

The data ruled out the DNA damage response, demonstrated the involvement of p21Cip1 in a p53-independent manner, identified the TGFβ pathway genes CLU and TGFBI as markers of sensitivity to decitabine and revealed an effect on histone modification as part of decitabine-induced gene expression.

We performed a high throughput combination screen on a large panel of cell lines and searched for markers of sensitivity or resistance.

Potential markers of sensitivity and resistance to targeted agents can be tested at the bench on the basis of these findings.

In addition to subjective response to alcohol, other biological markers of sensitivity have been studied in groups that differ for their risk of developing AUDs.