Sentence examples for marker of responsiveness from inspiring English sources
These studies used the C5 response to inhaled capsaicin as their marker of responsiveness rather than the C2 response where the difference between patients and control subjects was less evident.
However, the major interest in HER-2/ neu amplification lies in its utility as a predictive marker of responsiveness to therapy [ 11] primarily, the response of breast cancer patients to chemotherapy, hormonal therapy (antiestrogens) and therapeutic anti-HER-2 antibodies.
Elevated plasma sC5b-9 levels are reported as a potential marker of responsiveness.
Leptin can be used as an indirect marker of responsiveness, in fat tissue either mirroring nutritional status or as a sign of GHD.
This observation highlights the need for a reliable marker of responsiveness to MEK inhibitors, allowing tailoring of individualised therapies and reducing the occurrence of adverse events.
The association of pAKT and pERK in relation to response to ErbB-targeted therapy in ovarian cancer has not been studied yet, but expression of these proteins might be used as a marker of responsiveness to targeted therapies.
The aim of this study was to investigate the prognostic significance of bax, cytochrome c, and caspase-8 protein expression in a group of surgically treated patients to determine whether they also suggest markers of responsiveness to adjuvant radiotherapy.
The importance of pAKT and pERK expression as downstream markers of responsiveness to receptor tyrosine kinase-targeted therapies deserves to be evaluated in clinical trials.
Because response to treatment likely depends on polymorphisms at multiple loci [ 15], genome-wide analysis of gene expression with cDNA arrays has been recently used to identify markers of responsiveness in the peripheral blood mononuclear cells (PBMCs).
By contrast, other rare mutations such as the insertion in exon 19 recently described by Otto and co-workers [ 27], which is not recognizable by our actual NDO protocol, needs to be further validated in the clinical practice as markers of responsiveness to TKI therapy.
To date, PPV is the marker of preload responsiveness that has accumulated the largest amount of evidence [14, 23, 24].
