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Integration can be detected from pap smear or biopsy and use as marker of progressive disease.
Previous MRI studies by Welch et al demonstrated that PAG iron levels are abnormally high both in episodic and chronic migraine, suggesting the hypothesis that iron accumulation may be a marker of progressive PAG dysfunction.
In humans, tubular overactivation of AP-1 was described as a marker of progressive renal disease.
Spirometry is an insensitive marker of progressive lung disease, which is evident using high-resolution computed tomography (HRCT) [ 6].
Some authors considered the presence of sleep disorders as an earlier marker of progressive brain stem dysfunction.
Our results suggest that TRAP could serve as a marker of progressive disease, rather than being a selective marker of bone metastasis.
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Sleep length and architecture are potential markers of progressive cognitive impairment, while neuropsychiatric symptoms and APOE4− haplotypes have been associated with more sleep complaints in patients with dementia due to Alzheimer's disease (AD).
GAP-43 proteins are not only associated with intrinsic epileptogenicity but may be markers of progressive epilepsy and predictors of postoperative seizure outcome in patients with pharmacoresistant epilepsy due to FCD IIA/B.
These findings define the earliest identifiable markers of progressive post-traumatic epilepsy in the rat, with implications for mechanistic and prophylactic studies, and should prompt a re-evaluation of the concept of post-traumatic silent period in both animals and humans.
Together, these results highlighted the epigenetic RELB silencing as a new marker of the progressive disease in males.
Albuminuria has been considered a risk marker for progressive loss of renal function in type 2 diabetes with nephropathy, as well as a target for therapy (22).
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