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Loss of nuclear PAD2 expression may therefore represent a marker of progression towards more aggressive neoplasia.
The switch in TGFβ responses from growth-suppressive to EMT-inducing involves a change from Smad-dependent to Smad-independent signaling [24] and appears to be a critical marker of progression in HPV-mediated HNC and EMT.
If there is such a relationship, virus expression and mutation could be a marker of progression, perhaps a manifestation of lymphocyte activation [33].
TRAP might be useful as a marker of progression of malignant disease.
We also wanted to investigate p53 immunoreactivity as a marker of progression to invasion.
MMP1 has also been proposed as a marker of progression into BRC [ 61].
Similar(30)
Our findings are the first to suggest that the C677T MTHFR polymorphism plays a role as a predictive marker of progression-free survival in patients with metastatic colon cancer treated with 5FU/FA.
Increased EGFR gene copy number as determined by fluorescence in situ hybridisation (FISH) is known as a prognostic marker of progression-free survival and overall survival in HNSCC [ 11, 12].
We found image-based evidence that some in situ mammary cancers did not progress to invasive cancers, and investigated potential predictive markers of progression.
Our data raise potential caveats for the search of markers of progression.
Weiss, MF, Rodby, RA, Justice, AC, and Hricik, DE. "Free pentosidine and neopterin as markers of progression rate in diabetic nephropathy.
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