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Likewise, CD62L (SELL), expressed on classical monocytes, is an important early marker of progenitor cell commitment to specific progeny [30,31].
The transitional zone consisted of scattered carcinoma cells expressing vimentin or p63, a marker of progenitor cells associated with inhibition of EMT-positive cells in the transitional zone [12].
c-Kit+ cells obtained from in vitro culture did not possess KDR surface marker of progenitor endothelial cells (Fig. 5a).
Since CD34 has been characterized as a marker of progenitor cells in several lineages, it may represent another subpopulation of CPC or yet another lineage.
©2011 Wiley Periodicals, Inc. SOX2 (MIM# 184429), a member of the SOXB1 family of transcription factors, is a widely expressed marker of progenitor and stem cells.
The receptor for Ang-1, Tie-2, is observed in the surrounding mesenchyme, an area that also expresses CD34, a marker of progenitor vascular endothelial cells.
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AmphiGli-L was however unable to induce ectopic Nkx2.2 expression, a marker of progenitors ventral to the motor neurons that requires high levels of Shh signalling for its induction (Fig. 4K M).
Whereas WAPs expressing PDGFR β (the population targeted by D-WAT) give rise to white adipocytes, PDGFR α was revealed as a marker of progenitors capable of differentiating into both white and brown-like adipocytes.
Kidneys, liver, spleen, and heart were excised to quantify the expression of angiogenic mediators and markers of progenitor cells.
ELP-VEGF accumulated predominantly in the kidney and stimulated renal blood flow, glomerular filtration rate, improved cortical microvascular density, and renal fibrosis, and was accompanied by enhanced renal expression of VEGF, downstream mediators of VEGF signaling, and markers of progenitor cells compared to placebo.
Finally βlow-cells expressed high levels of markers of progenitor cells Ngn3 and Tcf7l2 [30] while islet-associated transcription factors such as Neurod1, Pdx1, Nkx6.1, Pax6 were downregulated.
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