We used DNA microarrays, tandem mass spectroscopy proteomics and bioinformatics to identify genomic and proteomic markers of mild and moderate/severe CAN in peripheral blood of two distinct cohorts (n = 77 total) of kidney transplant patients with biopsy-documented histology.
Creatinine levels were not significantly different between the IR and IPC-IR group, perhaps because creatinine and BUN are not sensitive markers of mild alterations in renal function.
18. Hammerer-Lercher A, Ludwig W, Falkensammer G, Muller S, Neubauer E, Puschendorf B, et al. Natriuretic Peptides as Markers of Mild Forms of Left Ventricular Dysfunction: Effects of Assays on Diagnostic Performance of Markers.
We model the effect of combined pathology in Fig. 3B as a decrease in the temporal separation between the Aβ amyloid curve and the complex comprised of the brain atrophy curve and the vertical markers indicating time-of-mild cognitive impairment and dementia diagnoses.
The NMR chemical shift δ = 3.599 ppm could potentially be used as a marker for mild forms of perturbations in the ammonia metabolism caused by genetic variations in the CPS1 locus.
As expected from the single-marker performance, the identification of mild current-activity synovitis (RA patients) was even better when combining markers into panels (Table 3 and Figure 2, right panel).
The primary goal of ADNI has been to test whether serial magnetic resonance imaging (MRI), positron emission tomography (PET), other biological markers, and the progression of mild cognitive impairment (MCI) and early Alzheimer's disease (AD).
The primary goal of ADNI has been to test whether serial magnetic resonance imaging, positron emission tomography, other biological markers, and the progression of mild cognitive impairment and early Alzheimer's disease.
It has been proposed that mild abnormalities could be a marker of disease, whereas severe potassium derangements could be a cause of mortality [ 5].
