The MeSy patients treated with HSEP had significantly reduced glucose and total cholesterol levels, increased HDL-c levels, and an improved TAG/HDL-c ratio, a marker of insulin resistance (t-test p<0.05).
Our results support the potential of white blood cells as a proxy tissue for studying insulin signaling and may lead to development of a minimally invasive and direct marker of insulin resistance.
The homeostasis model assessment of insulin resistance (HOMA-IR) was used as a substituted marker of insulin resistance.
Our results provide new knowledge regarding the global alterations in serum metabolite profiles post RYGB and position nervonic acid as a possible marker of insulin sensitivity.
We have previously shown that male mice fed from conception to adulthood with a high soy-containing diet had reduced body weight, adiposity and a decrease in glucose intolerance, an early marker of insulin resistance and diabetes.
Further, because this ratio is consider a surrogate marker for insulin resistance in humans, it seems PIO levels here where within a therapeutically-relevant range, reducing an indirect, yet classic clinical marker of insulin resistance.
The observation of a nonsignificant trend of an independent association between OSA and triglicerydes/HDL ratio, a marker of insulin resistance, may be due to the lack of power to detect this difference.
IGFBP1 is a marker of insulin sensitivity.
We used insulin as our primary marker of insulin resistance.
Hyperinsulinemia is a marker of insulin resistance, a component of metabolic syndrome [ 30].
HOMA-IR is a measurable, validated surrogate marker of insulin resistance.
