Its role as a marker of infectious inflammation was reported repeatedly, and today PCT is assessed as a sensitive and specific marker of severe bacterial inflammation [ 1, 2].
In this context, the over expression of MyD88 could be interpreted more as a marker of infectious processes and viral replication than that of an effective antiviral response.
In 1993, Assicot and coworkers [ 17] demonstrated that serum PCT concentration was a marker of infectious states of bacterial origin in children, exhibiting a rapid decrease following antibiotic treatment.
In 1993 Assicot and coworkers [ 17] demonstrated the value of serum procalcitonin (PCT) as a marker of infectious states of bacterial orgin in neonates and infants, as well as the rapid decrease in its concentration with appropriate antibiotic treatment.
Procalcitonin (PCT), a relatively novel marker of infectious processes, has been shown to be associated with the severity of inflammation and prognosis during sepsis and septic shock [ 14- 16].
Because glucosuria was more strongly associated with confirmed LONS (either clinical sepsis or culture-proven sepsis) than with solely culture-proven LONS, it appears that (an increase in) glucosuria can possibly be regarded as a sign of stress and not as a specific marker of infectious sepsis.
