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PAI-1 is upregulated by inflammatory cytokines and may be considered as a marker of existing inflammatory process, although the underlying mechanism of this is not yet elucidated.
First, we have constructed new HIS2 - and ADE1 -marked shuttle vectors by replacing the yeast-selectable marker of existing pRS plasmids.
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Among the different classes of existing markers, single sequence repeat (SSR) markers are known to be optimal for plant breeding and several studies to develop the SSR markers for B. rapa have been reported.
The 80 selected lines (see Additional file 5) provided the most complete set of existing marker scores, and had the fewest heterozygous regions.
The development of novel disease resistance markers or the refinement of existing ones would benefit from the availability of highly polymorphic marker systems that generate codominant, more tightly linked, and broadly applicable markers.
The majority of existing markers developed in NLL are AFLPs, MFLPs and RFLPs [ 19].
A BLAST facility is provided to enable querying any sequences of interest against targets of existing markers.
One of the reasons for the poor outcome of PC is the lack of early detection markers and limited efficacy of existing treatment regimens.
Overall, the diagnosis of TBM still remains a major challenge due to inadequate current diagnostic methods and poor sensitivity and/or specificity of existing markers.
The serial samples available in screening trial biobanks are crucial in developing and validating such algorithms, which may improve the performance of existing markers.
In turn the initial approximation of the ellipse should be drawn and, if necessary, its image modified with the use of existing markers to allow its position to best correspond to the real outline of the drop on the image.
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