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We then took advantage of the specific and beneficial amplification of the SUL1 locus as an intrinsic marker of evolution to study and visualize clonal interference in evolving populations of yeast.
To clarify the ancestry and domestication of Cynara crops, recent studies made use of rDNA spacer sequences, since they are generally considered a good marker of evolution (Small et al., 2004).
Furthermore, if such sequences are retained, do they evolve at the same rate as the organism, but with enough changes over time, thereby enabling its use as a marker of evolution?
Moreover, the difference in introns and the presence of an intron in the same position in different Trx-1 genes of different organisms suggest that it was present in the ancestor; however more detailed studies should be done to use intron position as marker of evolution [ 28].
The aim of the present study was also to evaluate the usefulness of CD1a expression as a marker of evolution of the metaplastic lesions, as metaplasia has been regarded as a predisposing condition for the development of oesophageal Ca (Malhi-Chowla et al, 2000; Moreto, 2003).
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Using genetic mutations as stable markers of evolution, we reconstructed the phylogenetic lineage of the tumor.
These mutations can serve as stable markers of evolution for reconstructing the natural history of the tumor.
These variants are interesting as both markers of evolution and for their phenotypic effects (e.g. characteristic traits and diseases).
In our previous work, we reconstructed the evolution of breast cancer genomes using copy number alterations (CNAs) as stable markers of evolution [ 4, 5].
By assuming that mutational complexity increases over time, we can use mutations as stable markers of evolution to reconstruct the relative chronology of the mutations during the natural history of the disease.
It is instead an abstract variable whose significance is solely as a marker of the evolution of soil characteristics.
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