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Finally, we sought to determine if IVIg-related plasmacytosis could serve as a marker of effectiveness of this treatment.
Thus, we propose rs201739205 as a possible predictive SNP marker of effectiveness of preventive anticancer treatment among obese postmenopausal women (Table S1, Additional file 1).
These data are important firstly because they add further validity to changing Ki67 at 2 weeks being an intermediate marker of effectiveness, thereby supporting the use of this marker for drug development and studies of mechanisms of resistance.
Surrogate marker of effectiveness are satisfaction levels, pain score, and sedation score measured by questionnaires which have to be completed by both, patient and GE, and patients sweat production as a sign of stress response.
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Key markers of effectiveness were described to participants as joint idea development, joint decision making and joint research outputs.
The regimens compared are 10 mg/day or 70 mg/week; a 12% response was observed in the daily regimen versus 0% in the weekly one; there was a higher incidence of pneumonitis in the daily regimen (16% vs. 6%) and no biological markers of effectiveness.
ER expression is a predictive marker of the effectiveness of tamoxifen in the treatment of DCIS [ 31].
Previously, PRL has been used as a marker of the effectiveness of AMPT as an inhibitor of endogenous DA synthesis [ 35] because hypothalamic DA is known to inhibit PRL release at the level of the pituitary gland [ 36].
Finally, we propose a new evaluation marker of biological effectiveness named Evaluation of RBE ERBEE) by calculating the ratio of the gamma-H2AX induction following high-LET irradiation compared to low-LET as a function of time.
The primary outcome in Ravi 2004 was the number of days needed to return to work and this was considered a surrogate marker for effectiveness of treatment and well-being of the patient.
Coinfection with these viruses, especially with HCV, is a strong prognostic marker for effectiveness of antiretroviral treatment [ 6, 7].
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