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The variability of HR is a marker of dynamic load because it is sensitive and responsive to acute stress.
During exercise, inspiratory capacity (IC) was measured spirometrically at the same time points as a marker of dynamic hyperinflation.
In the present study we aim to determine whether N-terminal pro-brain natriuretic peptide (NT-pro-BNP) serves as a marker of dynamic risk stratification.
Several investigators have also detected the presence of intrinsic positive end-expiratory pressure (PEEP) as a marker of dynamic hyperinflation in ARDS patients [ 28, 30, 31].
Improvements, versus placebo, in IC at isotime (a marker of dynamic hyperinflation) were also similar between aclidinium 400 μg BID (155 mL), tiotropium 18 μg QD (180 190 mL) [ 10, 22], and glycopyrrolate 50 μg QD (200 mL) [ 13].
Saha et al. reported that LA strain is an integrated marker of dynamic LA function that shows high reproducibility and identifies patients who are at high clinical risk of thromboembolism as defined by CHADS2 score [38].
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Measurement of markers of dynamic expression of bone turnover, enables evaluation of changes over time versus assessment of static changes in bone physiology that could be observed via DXA [ 50] is a conferred added strength.
Combinations of different marker modalities – for instance, markers of dynamic turnover (typically biochemical markers) and assessment of current status (for example, by MRI) – may provide complementary information and thereby superior identification of progressors for clinical trial design.
However, we also noticed that, contrary to NDP52, these markers remained strongly associated with the SCV even at 4 h p.i. (Fig. 2), suggesting that NDP52 is likely a better marker of the dynamic regulation of membrane damage/healing at the surface of the SCVs than p62 or ubiquitin accumulation.
Thomas et al (2003) failed to demonstrate any significant changes by in vivo imaging with dynamic CT (marker of microvessel density), dynamic MRI (marker of tumour blood flow) or [F]FDG PET (measure of tumour glucose metabolism).
At the molecular level, increased α-tubulin acetylation is considered to be a marker of the reduced dynamic of microtubule.
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