Sentence examples for marker of altered from inspiring English sources

Similar mechanisms are possibly at work in SLE, and the anti-EA response is possibly a serological marker of altered viral behaviour in response to, rather than as a cause of, an altered immunological state.

Traditionally, the occurrence of albuminuria has been held as a marker of altered glomerular permeability, and the use of ALBU excretion has been well established as a diagnostic and prognostic marker to evaluate the severity degree of glomerular damage in the progression of chronic kidney disease [17].

We wanted to identify if any of the lipidomic changes in plasma could be used as a marker of altered gene expression in muscle in the high dose simvastatin intervention group.

They also exhibit reduced sensitivity to the induction of cytochrome P450 1a (CYP1A), a widely used marker of altered gene expression in response to these compounds.

The bone mineral density (BMD), generally measured to determine fracture risk clinically, was evaluated as a surrogate marker of altered morphology [ 11].

Thus, a profile or pattern of multiple physiological, metabolic and haematological variables may provide the most effective marker of altered homeostasis to allow an assessment of an animal's response to transport.

SnoN protein not only paralleled the autophagy marker (LC3-II) but knockdown of SnoN altered LC3-II/I ratios suggesting that this protein lies downstream to SnoN.

We sought to examine the relative impact of various pollutant atmospheres and specific individual components on these markers of altered vascular transcription and lipid peroxidation.

FTIR and XAS are well suited to study markers of altered metabolism such as lactate and creatine (FTIR) and markers of oxidative stress such as aggregated proteins (FTIR) and altered thiol redox (XAS).

Dermatoglyphic patterns form on the finger pad and on the palm by the end of the second trimester and remained unchanged thereafter [ 4, 5], thus these features may serve as proxy markers of altered early development in psychosis [ 6, 7].

In the present study we used this established model of OA to study the changes in expression of key structural molecules (aggrecan and type II collagen), the collagen-associated SLRPs (biglycan, decorin, lumican and fibromodulin), TGF-β1 and its associated downstream signaling molecule connective tissue growth factor (CTGF), and markers of altered chondrocyte phenotype – types I and III collagen.