Sentence examples for marker of aggressiveness from inspiring English sources

MIB-1 and p53 expression has been reported as a marker of aggressiveness in many tumors.

In particular, magnetic resonance spectroscopy imaging (MRSI) has been used for tumor characterization: the relative ratio of (choline + creatine) over citrate has been seen as a marker of aggressiveness [59, 63].

HER2 is a marker of aggressiveness, the overexpression of HER2 gene increases the cellular growth and metastatic potentialities.

The positivity for this ligand/receptor pair is considered to be a marker of aggressiveness and unfavorable tumor outcome.

Although PAI-1 inhibits proteolytic activity of uPA, this molecule seems to be a marker of aggressiveness in malignant tumours.

Our data also demonstrated a significant association of the expression of NIS protein with lymphovascular invasion, a well-known marker of aggressiveness.

In conclusion, improved technologies and multimodalities, such as multiparametric MR + PET and dynamic PET, could be useful investigative tools, together with more specific PET tracers, in the search for markers of aggressiveness [64].

Most proposed mechanisms point to markers of aggressiveness or extent of disease spread.

Also, loss of ER-α and PR is associated with markers of aggressiveness such as age, myometrial infiltration and lymph node status [ 37, 50].

Indeed, syndecan-1 and syndecan-4, two cell surface HSPG that have recently been characterized as markers of aggressiveness in breast carcinoma, are overexpressed in estrogen-negative and highly proliferative carcinomas of the mammary gland [ 41, 46, 47].

Medical records were revised; patient's age, tumor size, axillary lymph node involvement, risk group, pathological staging of tumor and lymph nodes and clinical evaluation for metastasis (pT pN cM) were determined as markers of aggressiveness.