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Importantly, results in each proarrhythmic surrogate marker obtained by the exposure-response modeling also showed high similarity to those obtained by the E14 statistical evaluation.
In the present study, we introduce a new NHL diagnostic marker obtained by translating the information in low-mass ions (i.e., < 1000 m/z) in urine samples from lymphoma patients.
An alternative would be to use data from a historical randomised trial with the addition of results for a marker obtained by retrospective histopathological assessment of archived tissue, although this approach is very rare.
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Interval mapping, followed by multiple QTL model analysis, using the best markers obtained by interval mapping as co-factors, was used for normally distributed quantitative traits.
Linear combinations of diagnostic markers obtained by LDA or DF approach usually lead to higher discriminate powers (larger AUC) than with its individual components.
For comparison, we also show the mutation rates found by Zhivotovsky et al. (2003), which are based on a subset of the CEPH-HGDP markers obtained by removing markers with extreme variances.
In summary, we could infer the structural features of chromosome 6B with high resolution based on the the physical localizations of genic markers obtained by RH mapping (Fig. 3e).
The Lod scores between the brown phenotype and FH2319 and REN105I03 markers obtained by a two-point analysis on the complete pedigree, were 7.2 and 3.5 respectively, with a recombination fraction of θ = 0.
Thirdly, DNA markers obtained by our marker development strategy are all co-dominant, which can readily be converted into cost-effective, simple PCR-based markers desirable for high throughput implementation on modern SNP genotyping platforms for marker-assisted selection in molecular plant breeding.
The genome-wide and abundant EST-based SSRs and SNPs/Indels markers obtained by next-generation sequencing represent an effective approach to marker discovery in many plant species, as these markers facilitate generation of dense genetic maps and have the advantage of higher cross-species transferability [ 6, 39- 41].
The compounds were obtained by one-step conjugation between commercial peptides or by following standard and reliable synthetic procedures (peptide synthesis, amino group labelling and disulfide exchange); this is one advantage compared to other actin markers obtained by complex multistep organic syntheses.
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