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In addition, plasma cf-DNA levels were positively correlated with the abdominal aortic aneurysm diameter, suggesting that this marker may reflect the biological activity of the aneurysm and neutrophil activation in particular.
Similarly for FL, our detected reduced expression of CD163, a macrophage marker, may reflect a low number of macrophages present in the node microenvironment in many cases of FL.
Rather than considering that the unreliability of plaque as a disease marker may reflect badly on the amyloid hypothesis, its guardians embraced soluble Aβ oligomers as a cause of AD [ 100].
This marker may reflect variation at another adaptive trait that is part of the 'migratory gene package' or it could represent a false positive and thus be biologically irrelevant.
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Further, the silencing of immune cell markers may reflect the progression of central necrosis at this time, causing the death of macrophages and lymphocytes.
The expression of these markers may reflect neuronal changes associated with regeneration and possibly memory performance warranting future correlation studies with the cognitive status information in individual AD patients.
Plasma levels of serum tumour markers may reflect both stage of disease and prognosis.
This difference suggests that the markers may reflect different collagenolytic pathways, which possibly respond differently to oestrogens.
While serum markers may reflect clinical outcome, their clinical importance as an appropriate endpoint remains open to debate [ 88].
23 However, clinicians must be aware that abnormal concentrations of these markers may reflect advanced stages of PEI.
Therefore, the more pronounced effects of PM2.5 on these cell-surface markers may reflect an enhanced underlying inflammation and a reduced ability to cope with PM-induced inflammation.
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