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Because no single phenotypic marker is known to identify mature tenocytes conclusively, we utilized a combination of genetic and morphologic traits to assess tenocytic differentiation in response to BMP-12.
Because of this diversity, no general pan-pericytic marker is known (3).
The CD90 marker is known to be expressed by hematopoietic progenitors with the highest proliferative potential in vitro [ 28– 30].
This surface marker is known to be necessary for cells to migrate in and out of lymph nodes.
This genetic marker is known to be important for other human Transmissible Spongiform Encephalopathies (TSEs) including sporadic CJD, iatrogenic CJD and kuru [ 16- 18].
Even for the case of trastuzamab, where a single diagnostic marker is known, the most appropriate assay is still unclear, with a combination of two assays defining the current clinical practice.
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Here, using a 2 × 3 chi-square test, we describe a relationship between genotype-imputation error rates and the sample-size inflation required for achieving statistical power at an imputed marker equal to that obtained if genotypes at the marker were known with certainty.
Seven variants of this marker are known enabling the discrimination between low, intermediate and high AAC genotypes (Ayres et al. 1997; Shu et al. 1999; Bergman et al. 2001; Tan and Zhang 2001).
In addition, urinary estrone-3-glucuronide (E3G) was analysed as a marker of estrogen status as levels of this marker are known to be associated with depression and anxiety (Lokuge et al., 2011).
This is expected because F ST estimated from highly variable markers is known to bias estimates downwards.
The setting in which one wants to consider the addition of a new marker to an existing set of markers is known as a nested model.
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