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In line with recent recommendations by Little (2013), we used the effect coding method (instead of fixing the latent construct's variance at 1 or the marker indicator) to identify the model.
Lastly, we underscore the role of SOX2 in the clinic and highlight new findings, which may provide novel clinical applications for SOX2 as a prognostic marker, indicator of metastasis, biomarker or potential therapeutic target in some cancer types.
As with other confirmatory factor analyses (CFA), the first OES item in each factor was used as marker indicator for the latent factor.
Here, we report the consequences of RUNX1-CBFA2T1 depletion on CD34 expression (a surface marker, indicator of differentiation), for the proliferation and clonogenicity of in t(8 21 -positive leukaemic cell lines.
We used the same assay to track huntingtin siRNA effects on a cell-by-cell basis using a siRNA transfection fluorescent marker indicator Block-it™ Block-it™luor Red) in our mCeruleAlexaFluor stable STHdhQ7/Q7 cell line (Fig. 4Ca–b and h–i).
As a prerequisite for analyses in Mplus 6.12, the item with the highest loading on the respective factor in an exploratory factor analysis using Principal Axis extraction (not reported here) was chosen to be the factor's marker indicator, i.e. their factor loading being fixed to one.
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The items with the highest salient loading on their respective factor were chosen to be marker indicators.
This result is intuitive also, since marker indicators are expected to reach the value 1 more easily, when the interval (− b, b) is shortened.
Items 3, 13 and 34 were chosen to be marker indicators since these items had the highest salient loadings on their respective latent factors.
Although there are differences in the UCC smoking rate, the adjusted UCC smoking rate, the SRs + UCC smoking rate, and the adjusted SRs + UCC smoking rate, all of the biological marker indicators exhibit a decreasing trend in smoking.
Biomarkers (also termed chemical fossils, molecular markers, indicators or organic tracers) are specific organic compounds which are useful in assessing the genetic sources of lipidic or bituminous organic matter.
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