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Up to now, Breslow tumour thickness is still the best prognostic marker in primary melanoma.
To our knowledge CD163 has not been evaluated as a TAM marker in primary breast cancer.
HER-2 is a valuable therapeutic and prognostic marker in primary breast carcinomas [ 10].
We tested Ki-67 proliferation marker in primary and lymph node metastasis of CRC.
Our findings suggest that M3H67 immunoreactivity could serve as potential prognostic marker in primary breast cancer patients.
To the best of our knowledge, CD163 has not been evaluated as an M2 macrophage marker in primary OSCC.
Similar(51)
Confirming our results obtained with the TUNEL assay, no evidence of accumulation of these apoptotic markers was detected in primary motor neurons despite the clear neurite degeneration phenotype (Fig. 7B).
In addition, silk proteins also induced the expression of osteoblast markers in primary rat bone marrow cells isolated from tibiae.
PEDF has also been identified as a niche signal for neural stem cell self-renewal and can induce cone photoreceptor markers in primary retinal neural aggregates [28] [30].
Furthermore, higher expression of differentiation markers in primary AML cells with oncogenic N-RAS mutations (Figure 5E) strongly suggests that mutant H-Ras and N-Ras function similarly to promote differentiation in hematopoietic cells.
Moreover, some of the histological markers in primary lung adenocarcinomas have prognostic impact.
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CEO of Professional Science Editing for Scientists @ prosciediting.com