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The present study was designed to evaluate the possible effects of the JAK/STAT, TNF-α, and NFκB pathways, and the caspase-3 apoptotic marker in human colorectal tissue.
In the following, we will discuss: 1) Plasma PACAP38 as a biochemical marker in human experimental models; 2) heterogeneity of the PACAP38 response in MO patients; 3) MRA biomarkers of PACAP38-induced migraine-like attacks; 4) future experimental models using PACAP27.
Taken together, we conclude that MST2 is a bona fide substrate of Akt and that pMST2-T117 could be a prognostic marker in human breast cancer.
Ki-67 is a granular component of the nucleolus that is expressed exclusively in proliferating cells and is used as a prognostic marker in human neoplasias.
Although the specific function of TDP-43 is not clear, its cytoplasmic accumulation in skeletal muscle tissue has been used as a disease marker in human myopathies [8].
However, γ-H2AX staining was not observed in untreated MEF and ES cells, justifying the use of γ-H2AX as a DSB marker in human ES cells.
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SSEA-4 is an embryonic stem cell marker in humans but it is not present in mouse embryonic stem cell lines, which are instead positive for SSEA-1.
We recognize that tryptase is not the only MC marker in humans.
The overexpression of ROBO1 in HCC was recently reported and this receptor was proposed as an HCC marker in humans [ 19].
In addition, CD5 can be regarded as a B-cell activation marker in humans and there are no convincing data providing evidence that it can be used as a lineage marker as accepted in mice.
He and other geneticists have identified genealogical markers in human DNA that record the spread of humans around the world.
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