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ALDHI has been used as a marker in detection of breast cancer stem cells [67]– [69] and, more recently, in lung cancer [70].
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The changes in the distribution of DNA, lipids and proteins in the cells during the process of carcinogenesis could be early markers in detection of high-risk patients before morphological changes occur.
Therefore, we designed this study, including an exploratory and a validation study, in order to further assess the performance of SEPT9 methylated DNA as a marker in the detection of colorectal precancerous lesions.
Our results suggest that telomerase activation is common in NPC and it may be useful as a diagnostic marker in the detection of tumour cells in nasopharyngeal biopsies.
We obtained more interesting results with BSP, a protein produced by osteoblasts, whose expression is increased in osteosarcoma patients; nevertheless, quantitative difference between the two groups is not wide enough to use this molecule as a single marker in the detection of peripheral micrometastasis.
In research, the division supports investigations into the cellular biology of brain cells and brain cancers, the role of imaging and cell markers in early detection of brain cancers, and whole-genome analysis of gliomas and other cancers.
The aim of this study was to compare efficiency of biochemical bone markers in the detection of bone metastases in lung cancer patients.
These qualities make CD34 and CD31 suboptimal markers in the detection of LVI in cutaneous melanoma.
DNA methylation changes are widely used as early molecular markers in cancer detection.
Their roles in these biochemical pathways make them useful markers in the detection of stress in plant metabolism.
Further study using larger cohorts is needed to evaluate the potential use of these methylation markers in the detection, prognosis and therapeutic outcome of this rare tumour.
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