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Ten or fewer marker genotypes were missing in 91% of the genotyped individuals.
However, after removing SNPs that were monomorphic, had too much missing data (>15% of population size), or the marker genotypes were not described in the JoinMap® v4.1 manual50, we retained ~7000 SNPs per population.
The data for marker genotypes were simulated in terms of the recombinant homozygote proportion (R).
For each marker, genotypes were scored automatically using GeneMapper 3.7 (Applied Biosystems) and manually verified and corrected in case of automatic scoring errors.
All ambiguous marker genotypes were deleted.
The marker genotypes were compared with the PhtjR gene phenotypes.
Similar(34)
Different from the backcross population, the conditional probabilities of a QTL genotype given marker genotypes are expressed in terms of the proportion of recombinant homozygotes [57].
These markers, combined with the male-inherited component of the 3∶1 marker genotypes, are used for constructing the final linkage map [25], [26], [36].
This method also allows the use of an empirical variance-covariance estimator for the statistic, which is consistent when sibling marker genotypes are correlated (e.g. when the analysis includes multiple affected sibs) [55].
With GBS, several marker genotypes are missing and, even after imputation, uncalled genotypes are still present.
When disequilibrium is complete and all marker genotypes are observed, E Q | M ) = Q.
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