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Urinary density (UD) has been routinely used for decades as a surrogate marker for urine osmolality (Uosm).
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We previously reported a panel of TMPRSS2 ERG fusion-subtype markers for urine-based cancer detection with high specificity and sensitivity [ 30].
We are among the first to use a panel of TMPRSS2 ERG subtype markers for urine-based prostate cancer detection with high specificity and sensitivity [ 30].
In addition, we adjusted for urinary creatinine concentration (continuous, nontransformed) as a marker of urine dilution.
Urine density has long been considered as a practical surrogate marker of urine osmolality.
While this prediction program has been applied to gastric cancer data in this study, no gastric cancer-specific information was used in this program; hence, it can be used for urine marker searches for other diseases.
Furthermore, HX identified in the study may be a useful single urine marker for NHL screening.
Furthermore, hypoxanthine identified in this study may be a useful single urine marker for NHL screening.
Teratani et al. [ 32] suggested the use of B-FABP transcripts as a novel urine marker for early detection of RCC and for monitoring RCC patients postoperatively.
As, Ta tumours showed a high KRT7 expression we examined the potential of KRT7 as a new urine marker for early bladder cancer.
Even though cancer cells in bladder tumours strongly expresses KRT7 protein, it cannot be used as a new urine marker for bladder cancer within this setup.
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