Sentence examples for marker for unfavourable from inspiring English sources

In other types of cancer, HIF-1α was a marker for unfavourable prognosis, such as in early-stage invasive cervical cancer.

To identify patients with a high risk of recurrence of oesophageal squamous cell carcinoma, we investigated the prognostic significance of survivin mRNA expression in oesophageal squamous cell carcinoma, which has recently been reported to be a good marker for unfavourable prognosis in various tumours.

In addition, overexpression of ID-1 has been indicated as a marker for unfavourable prognosis in breast cancer (Ling et al, 2005), and the level of ID-1 protein expression is correlated with a more aggressive clinical behaviour of ovarian and prostate carcinomas (Schindl et al, 2003; Schoppmann et al, 2003).

Further analysis of the pivotal National Surgical Adjuvant Breast and Bowel Project B06 trial showed that local recurrence was a strong predictor of reduced survival, but it seemed to act as a marker for unfavourable disease rather than as a source for the development of metastases [ 10].

Interestingly, in the present and to date most comprehensive study of KRAS alterations in primary and metastatic lesions from endometrial carcinoma patients, we find that high KRAS mRNA expression and KRAS amplification, in contrast to KRAS mutation, are associated with a large range of surrogate markers for unfavourable outcome and poor disease-specific survival.

Data from this study suggest that PRMT1 gene variant v1 expression may be used as a marker of unfavourable prognosis for colon cancer patients.

Additionally, ADAM9 expression is significantly associated with markers of unfavourable prognosis.

We have shown for the first time that tumoral CD105 is an independent predictive marker for death risk and unfavourable prognosis in patients with ccRCC after curative resection.

Summarising, miR-145 proved to be an independent unfavourable marker for the disease progression and the DFS expectancy of the 'low-and intermediate-recurrence risk' PCa patients.

Hence, miR-9 might be considered as a candidate marker predicting unfavourable prognosis for patients with paediatric MB that deserves further validation studies.

We here identified EZH2 expression as a novel, powerful, and independent unfavourable prognostic marker for CSS in patients with both metastatic and non-metastatic RCC.