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Consistent with the C3 and C5a ELISA data, increased levels of the C3 beta chain, which is not proteolytically processed and serves as a marker for total C3 levels, and iC3b, which is derived from the proteolysis of the C3 alpha chain and serves as a marker of complement activation, were detected in BAL collected from mice inoculated with H5N1 VN/1194.
Serum PSA, a surrogate marker for total body prostate tumor cell burden [25], was used to confirm the anti-tumor effects and was significantly lower ( p<0.001 vs. dual control; One way ANOVA and Bonferroni's post-hoc analysis) in 225Ac-E4G10 treanimalsimass as compared to the controls (Fig. 2D).
The myosin-V immunohistochemistry technique is a marker for total neuronal population.
PFOS serum concentrations can be used as a marker for total exposure in occupational medical surveillance studies.
Similar results were found for pre- and postnatal CB-153 exposure, a good marker for total PCB exposure.
Although increases were also seen for DNA content, the marker for total neural cell numbers, there were significant regional distinctions.
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An alternative to the application of FIB would be genetic markers for total fecal pollution.
In addition several markers for total fecal pollution have also been proposed.
The oral and dermal toxicological reference values for the PAHs are for the sum total of the eight PAHs included in REACH Annex XVII entry 50 (ECHA-8) as marker for the total PAH mixture in rubber granulate.
For inhalation, the toxicological reference value of 1 ng/m3 relates to an additional cancer risk of 1 × 10−4, with BaP as marker for the total PAH mixture in air.
Two hundred forty-four articles report for the first time at least one new mRNA or protein marker for a total of 380 markers.
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