Exact(4)
First, CTC can survive chemotherapy and therefore can be a predictive marker for the effectiveness of treatment.
BUN, a waste product of protein catabolism, has been extensively studied in dialysis patients and is an important target for removal by (hemo) dialysis, as well as a marker for the effectiveness of dialysis.
Combined, our data suggest that endotrophin levels are a strong prognostic marker for the effectiveness of the combination therapy of TZDs with cisplatin, and neutralization of endotrophin activity dramatically improves the therapeutic response to combination therapy.
This protein can bind pRB and there is a report that E2F4 expression level is a useful predictive marker for the effectiveness of intravesical BCG therapy that can predict clinical outcomes, including recurrence, progression, and survival in patients with BC [ 26].
Similar(56)
In colorectal cancer, both intratumoural TS and DPD gene expression have been indicated to be positive predictive markers for the effectiveness of 5-FU or UFT combined with leucovorin (Salonga et al, 2000; Ichikawa et al, 2003).
In consideration of the suspected pathogenic proinflammatory effect of PGRN Abs disrupting the physiologic homeostasis of TNF-α/PGRN agonists and antagonists in a subgroup of patients with PsA, PGRN Abs might be of use as prognostic markers for the course of disease and/or as predictive markers for the effectiveness of TNF-α-blocking agents.
Therefore, some authors have proposed that the Disease Activity Score in 28 Joints (DAS28) is an inappropriate marker for assessing the effectiveness of TCZ therapy for patients with RA [ 5– 7].
The level of TSH receptor antibody (TRAb) has proven to be a good marker for monitoring the effectiveness of treatment and predicting cases of relapse and remission, especially with the developed functional thyroid-stimulating autoantibodies (TSAb) assay reported in 2012 199).
Another important goal is to identify the biomarker providing the most accurate information about the quantitative extension of brain damage and representing a reliable marker for the evaluation of therapy effectiveness [ 6].
This paper describes a useful serological marker system for monitoring the effectiveness of drug treatment in Chagas disease, and a tool that may well allow early detection of therapeutic failure.
It remains unknown whether change in MPD with AI therapy may be a useful early marker for monitoring effectiveness of adjuvant treatment.
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