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SAA, the mouse counterpart of human C-reactive protein, is an acute phase reactant known as a marker for systemic inflammation.
The frequency of Th17 cells in SF correlates significantly with CRP, a marker for systemic inflammation, suggesting that local Th17 cells contribute to active disease.
Neutralization of type-I IFNs, using an anti-IFN-α/β serum, completely inhibited Ly6AE upregulation on peripheral blood CD8 T cells (Figure 2A), confirming our previous finding that upregulation of Ly6AE expression is a bona fide marker for systemic type-I IFN release [5], [23].
PAD is considered a marker for systemic atherosclerotic disease.
CRP is a sensitive marker for systemic inflammation.
Microalbuminuria is recognized as a surrogate marker for systemic endothelial dysfunction [ 40].
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However, most previous studies evaluated only downstream markers for systemic inflammatory responses.
CRP and leukocyte counts were measured as markers for systemic inflammation but no significant differences were found.
Our results demonstrate that the markers for systemic inflammation can return to normal despite no clinical improvement.
Anti-Sm antibodies, identified in 1966 by Tan and Kunkel, are highly specific serological markers for systemic lupus erythrematosus (SLE).
Data on levels of blood markers for systemic inflammation high-sensitivity C-reactinflammation high-sensitivitygen—were available for 22,561 and 17,428 persons, respectively.
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