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Consequently, HER2 overexpression does not represent a reliable predictive marker for responsiveness to Herceptin™.
The key enzyme OTC and ASS of urea cycle could be regarded as an effective predictive marker for responsiveness to rhArg therapy, which facilitates pretreatment screening.
To investigate the potential role of HER2 as a predictive marker for responsiveness to EGFR targeted therapies, we developed a series of MCF7 breast cancer cell line subclones that express graded levels of HER2.
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Although tumour size and international federation of gynaecology and obstetrics (FIGO) stage may serve successfully as markers for responsiveness to radiotherapy, they are not likely to fully account for the observed variability.
The objective of this study was to evaluate basal anti-Müllerian hormone as a marker for ovarian responsiveness to fertility treatment.
We hypothesize that even in this setting measurement of CD127 expression on CD8+ T-cells may prove to be clinically useful marker for predicting responsiveness to IL-7 administration.
This indicates that the baseline expression levels of the selected set of 15 IFN-induced genes can be used as a predictive marker for the responsiveness to IFNß treatment.
This meta-analysis was performed to evaluate the relation between ACE I/D gene polymorphism and treatment response to steroid in Asian children and to explore whether ACE D allele or DD genotype could become a predictive marker for steroid responsiveness.
Progesterone receptor status is a marker for hormone responsiveness and disease prognosis in breast cancer.
Thus, E-cadherin expression levels could constitute an important predictive marker for the responsiveness to microtubule-targeting VFL therapy.
On the basis of this finding, we hypothesize that survivin is a potential marker for predicting responsiveness to chemotherapy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com