The cells were stimulated with A23187, LPS or CD30, and the release of tryptase and IL-8 were measured as markers for reactivity towards stimuli.
However, the results from Zampetaki and colleagues [ 79, 81], as well as our independent work, indicate that circulating miR-223, presumably derived from platelets, may serve as a novel marker for platelet reactivity.
Indeed, in our study, by taking the intensity of normal colonic staining as a marker for tumour reactivity, we managed to identify four distinct patterns of Beclin 1 expression: underexpression of Beclin 1, which was evident in 15.5% of tumours, the normal-like pattern, which was present in 40.6%, and overexpression of Beclin 1, which was detected in the remaining 43.9% of cases.
As we show here, similarly TBB3 auto-antigen presence is a marker for CM and immune-reactivity of subjects can be used to classify different clinical forms of malaria as well as control groups.
Mental stress reliably induces increases in salivary alpha amylase (sAA), a suggested surrogate marker for sympathetic nervous system (SNS) reactivity.
Although this antigen is expressed by all cells of epithelial origin, the absence of maternal luminal/glandular epithelium during the final stages of gestation usually makes cytokeratin reactivity a suitable marker for locating extravillous trophoblast cells among the other decidual cells (decidual cells, stromal cells, macrophages, lymphocytes, and natural killer cells are cytokeratin-negative).
Although the sample size in the mRNA analysis was too small to make any final conclusions, we consider the semiquantitative assessment of immunostaining reactivity a more reliable marker for the actual protein expression level.
The entire specimen was scanned for reactivity.
Conclusions: Given the suggestive evidence in this study, prospective analyses to examine whether anti-Hu reactivity might predict risk of developing SCLC, or whether anti-Hu reactivity could serve as an early marker for SCLC, may be warranted.
Ideally, the PPD test could be used as a marker for tuberculosis infection, but unfortunately there is cross-reactivity between NTM infection and BCG vaccination [ 17– 17].
