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These rhNPC form neurospheres (Fig. 1A), which are more than 90% nestin positive (a marker for progenitor cells) (Fig. 1B).
One marker for progenitor cells is Nestin.
HCC expressing cytokeratin 19 (CK19), a potential marker for progenitor cells, have a worse prognosis.
These findings also pointed to Id1 as a selective marker for progenitor cells that could be used to identify EPCs in tissues characterized by extensive vascular remodeling.
Doublecortin and calcium/calmodulin-dependent protein kinase-like-1 (DCAMKL1) is a candidate marker for progenitor cells in the gastrointestinal mucosa.
Flk-1 is a receptor for vascular endothelial growth factor, and a marker for progenitor cells of hematopietic and endothelial lineage [ 26].
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These cells were subjected to immunohistochemical methods to measure the concentration of marker proteins for progenitor cells and cells in different phases of differentiation.
Thus, there are no definite markers for progenitors in adult fundic glands.
CK5 is a marker for mammary progenitor cells, CK14 is a marker for both mammary progenitor cells and mature myoepithelial cells and CK18 is an established marker for mature luminal epithelial cells [30].
Prominin-1 (CD133) was originally described in mouse embryos as a marker for neuroepithelial progenitor cells [9], and in humans as the AC133 antigen, a marker of hematopoietic stem and progenitor cells recognized by the monoclonal antibody (mAb) AC133 [10].
In murine embryonic kidneys, Six2 is considered a marker for these progenitor cells (Kobayashi et al., 2008), whereas, in human embryonic kidneys, NCAM1 was identified as a nephron progenitor marker (Harari-Steinberg et al., 2013).
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