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In this material, we only had mortality as a marker for morbidity in the LTC-groups making it difficult to compare groups of the same morbidity with high and low LTC with one another.
Increased levels of CFD have been detected in many pathological situations such as infection, inflammation, trauma, respiratory insufficiency, pulmonary embolism, autoimmune disease, sepsis, and cancer and have been found to be an adverse prognostic marker for morbidity and mortality [ 1– 6].
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CRP is not only a strong marker for cardiovascular morbidity but a modulator that suppresses local and systemic thromboregulatory pathways.
CRP is a sensitive indicator of active systemic inflammation and an independent risk marker for CV morbidity, including ischaemic stroke [41].
Anaemia is an independent risk marker for cardiovascular morbidity and mortality and it is a common complication in patients with chronic kidney disease (CKD) [ 1- 3].
Use of short-acting β-agonist, a marker for asthma morbidity [ 16], increased significantly in the year after switching among patients in the switched cohort relative to controls.
A high level of urine ACR, most likely representing excessive glomerular capillary leakage of albumin, 19 is a risk marker for cardiovascular morbidity and mortality 30 and is believed to reflect endothelial dysfunction.
In addition, the adjustment for key factors that could influence health care resource use, particularly the primary/secondary diagnosis and number of associated diagnoses, helps guard against the possibility that anemia is simply a marker for greater morbidity and severity of underlying disease.
WHtR has been suggested to be equal or superior to BMI as a marker for cardiometabolic morbidity later in life in children between 4 and 18 years, because children within the same BMI category but with larger waist circumference had higher risk of having metabolic syndrome, high diastolic blood pressure, and elevated insulin level (Maffeis et al. 2008; Mokha et al. 2010).
If this was true, LTC would be more than a marker for co-morbidity and hospitalization needs.
Aiming at finding sensitive and reliable biomarkers for P. vivax, herein we tested the usefulness of plasma CNAs levels as markers for the morbidity of vivax malaria.
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