Sentence examples for marker for mitosis from inspiring English sources

BrdU incorporation visualises DNA replication and Cyclin B degradation is a marker for mitosis.

Furthermore, staining of the cells with pH 3 (a marker for mitosis) showed that, as has been shown, knockdown of the SAC with BUBR1 shRNA decreased the percentage of cells in mitosis (Moffat et al. 2006).

Immunostaining of γH2AX (marker for double strand DNA breaks), pChk1S296 (marker of Chk1 activation), phistone H3 (marker for mitosis), cleaved caspase 3 (CC3) (marker for apoptosis), and pS6 were performed.

No significant differences were observed in immunohistochemical detection of phospho-histone H3, a well-established marker for mitosis, cleaved PARP, a marker for apoptosis, or the proliferation marker Ki67 between control tumours and the two therapeutic regimes: tumours from phenformin pre-treated mice and established tumours treated with phenformin.

In these experiments, tagged PICH-WT (or PICH-WAB for control) was isolated from 293 T cells that had been synchronized in mitosis or G1/S by treatment with nocodazole or thymidine, respectively, and cell cycle stages were confirmed by analysis of phosphohistone H3 staining (a marker for mitosis; Crosio et al. 2002) and responsiveness of PICH to Plk1 binding (Fig. S 4C).

Corresponding to these in vitro data, quantitative immunohistochemical analysis of the dissected tumor material from the HDAC8-inhibitor-treated mice revealed an increase in neurofilament-positive tumors (7/12=58.3%) compared with control groups (1/12=8.3%), and a significantly lower amount of cells positive for phosphorylated histone H3, a marker for mitosis.

Not surprisingly, markers for mitosis and Nimrod C rarely colocalized in cells of either genotype (Fig. 4G H1, arrow).

Phosphorylation of histone H3 at Ser10 is crucial for chromosome condensation and traditionally regarded as a marker of mitosis [ 2].

p16 expression also reduced staining for PCNA, another marker of S phase (Fig. S5a, Supporting information, P = 0.007; TetO-p16-2 line), and phospho-histone H3, a marker of mitosis (P-H3, Fig. S5b, Supporting information, P = 0.003; TetOp16-2 line).

Cells were harvested 1 h after treatment and analysed by flow cytometry for histone H3 phosphorylation as a marker for entry into mitosis.

It is also a marker for cells in mitosis.