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What is particularly important, the circadian components here mapped could serve as a marker for interventions, therapeutic or other.
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The slowing of EEG oscillations has been used as a marker for intervention effects in clinical trials, but the results have varied.
Also, the number of scheduled visits is not a direct marker for intervention intensity because a subject may have had a second visit scheduled because she missed the previous appointment.
BACKGROUND Chronic kidney disease (CKD) is an adverse prognostic marker for valve intervention patients; however, the prevalence and related outcomes of valvular heart disease in CKD patients is unknown.
Clinically, the total APA is often used as a marker for nutritional intervention.
In such cases, urinary phosphorus excretion per creatinine clearance could be a useful marker for early intervention for phosphate restriction because of its inexpensive and minimally invasive features.
What I'm hearing you say is that you need to specify a marker for the specific intervention that you're trying to study – that there needs to be some surrogate in there somewhere.
These types of analyses will not only facilitate development of unbiased hypotheses at the molecular level, but will also assist us in following the scent to the identification and characterization of novel targets and disease markers for pharmacological intervention, gene therapy and diagnosis.
We describe significant associations between frailty and microbiota diversity and composition, which represent potential diagnostic markers or therapeutic targets for interventions to reduce frailty in ageing.
If validated, this could be a useful marker for targeting smoking cessation interventions.
However, it is unclear whether the effects of social adversity on immune-related biomarkers are evident in early life, and if these biomarkers may provide an early risk marker for targeting prevention and intervention.
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CEO of Professional Science Editing for Scientists @ prosciediting.com