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To date, C-reactive protein and leukocytes are routinely used as the marker for infection or inflammation in our center.
T4SS (Type IV Secretion System) is an important virulent factor of Brucella and required for infection suggesting their expression in vivo and can be targeted as serological marker for infection.
Also, because neutrophils play an important role as primary phagocytes, neutrophil CD64 expression, a diagnostic marker for infection and sepsis [32], was measured on the blood sample used for cytometry using a Leuko64 kit (Trillium Diagnostic, Brewer, ME) containing fluorescent beads, CD64, and CD163 antibodies analyzed with a FC500 flow cytometer.
A GFP reporter driven by an independent murine 3-phosphoglycerate kinase promoter (PPGK) was used as a marker for infection.
The phenotype of the cells is maintained during disease progression, suggesting that it could serve as a marker for infection and probably contributes to the severe dysregulation of the immune system seen in AIDS.
ESAT-6, induced interferon (IFN γ) is considered to be a MTB specific marker for infection and disease as it is present only in the M. tuberculosis complex [10].
Similar(28)
Furthermore, abnormal CRP values as marker for infections were also more common within the secondary headache group.
Among a variety of related parameters, PMN migration proved to be a sensitive predictive marker for infections.
The impact of antibiotics on length of stay could originate from two pathways: a modification of the gut flora induced by the antibiotics or as a surrogate marker for infections.
Overall, our study highlights the usefulness of diversity measures as markers for infection age.
Additionally, non-specific markers for infection and inflammation, such as the acute phase proteins, are induced by the host [ 6].
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