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To date, no reliable serum marker for clear cell renal cell carcinoma (CCRCC) is available.
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Calura et al. analyzed miR profiles characteristic of each EOC histotype at stage 1 and found robust miR markers for clear cell and mucinous histotypes.
According to the ROC curves we found that the markers Napsin A, p21 + p53- and p21 + p53-Napsin A + all had some predictive value as diagnostic markers for clear cell ovarian carcinoma.
While basic research provides some evidence for both hypotheses, markers for the clear identification of islet cells that generate insulin-secreting progeny remain elusive.
The REMARK report stated the importance of transparent and complete reporting in the publication of research on tumour markers, highlighting the need for clear descriptions of patient and specimen characteristics, assay methods, study design and statistical analysis.
There is one clear marker for depression - suicide - and suicide rates have been recorded, with varying degrees of diligence, for centuries.
The substance -- a small, never-before-seen protein molecule -- may be a clear marker for mad cow disease and related ailments, a group of illnesses called prion diseases.
And they all contained a higher-than-terrestrial proportion of the oxygen-17 isotope, a clear marker for an origin in red giants, exhausted stars that lost their outer atmospheres to the cosmos.
Instead of being afraid of the slope, we must first examine the intrinsic merit of the suggested change, and second, notch the slope, set a clear marker for how far we are going to go and where the line which we are not going to cross is--newly drawn.
To analyze the mode of cell death, we performed Caspase-3 activation assays to distinguish between apoptosis and necrosis, since activation of this executioner caspase is a clear marker for apoptotic cell death.
In terms of TAP gain and expansion patterns, no clear marker for multicellularity emerges from our analyses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com