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rs266849 was initially identified in a GWAS using controls selected for low prostate-specific antigen (PSA) levels (<0.5 ng/ml) [4] and it has been suggested that rs266849 is a marker for circulating PSA levels rather than for prostate cancer risk [16], [17].
CD146 is a marker for circulating endothelial cells.
CRTH2 has been suggested to be the most reliable marker for circulating human Th2 cells [ 16].
Our study suggests that methylated RASSF1A DNA in serum is a surrogate marker for circulating neuroblastoma cells.
Recently, CD146 has also been described as a useful marker for circulating endothelial progenitor cells (Delorme et al. 2005).
Similarly microphthalmia TF has been reported as a marker for circulating tumor cell detection in blood of melanoma patients [ 26].
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Conclusions Increased LBP release at the onset of fever could account for marker of circulating endotoxin and the following inflammatory implications, in trauma patients hospitalized in ICU.
However, EGFR, a mRNA marker gene described for circulating tumour cell detection in peripheral blood of breast cancer patients (De Luca et al, 2000), appeared not to be applicable as a marker gene in lymph nodes due to its high background expression in control lymph nodes.
HbA1c is an important marker for overall circulating glucose levels, including the postprandial state.
The k-ras gene seems to be a good genetic marker for detecting circulating tumour cells from rectal cancer patients.
LSP-1 is a marker for fibrocytes — circulating bone marrow-derived mononuclear cells that have the capacity to deposit extracellular matrix in wound healing and numerous fibrotic disorders, including SSc [53].
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Justyna Jupowicz-Kozak
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