Sentence examples for marker for active from inspiring English sources

Previous studies have determined the position of centromeres for T. cruzi chromosomes by a functional mapping and measuring of topoisomerase II activity (a biochemical marker for active centromeres) (Obado et al., 2005, 2007) and T. brucei megabase chromosomes by topoisomerase II activity (Obado et al., 2007; Echeverry et al., 2012).

Nuschke et al. found that accumulation of cleaved type II light chain 3 (LC3-II) protein, a marker for active autophagosomes, was correlated with osteogenic differentiation, indicating activation of autophagy upon stimulation of differentiation (Nuschke et al., 2014).

There is also conjecture over whether H3.3 is not just a marker for active regions, but whether it contributes to the transcriptional activity of loci enriched for this histone (Huang and Zhu 2014).

As periarticular demineralization and joint damage are both related to imbalance in osteoclast and osteoblast activity, measures of hand bone loss may be a marker for active deterioration of bone and a predictor of subsequent erosive joint damage.

Therefore, the aim of this study is to define the prevalence and diagnostic value of autoantibodies against nucleosomes as a marker for active proliferative lupus nephritis.

Receiver operator characteristics (ROC) analysis revealed that frequencies of PPD specific IFN-γ/IL-2 dual-positive T cells below 56% were an accurate marker for active TB (specificity 100%, sensitivity 70%) enabling effective discrimination from non-active states.

We selected H3K4me3 and H3K27ac as markers for active genes and enhancers, H3K36me3 for actively transcribed regions and H3K27me3 as a mark for transcriptionally silent chromatin, and compared the results with public data.

No significant changes were seen for di and tri methylation of H3K4, markers for active chromatin conformation [41], [42].

In that study, ∼2700 of the assayed genes were found to have two opposite chromatin modifications in ES cells, H3K4Me2/Me3 and H3K27Me3, markers for active and silent chromatin, respectively.

For instance, both H3K4me2 and H3K4me3 are markers for active transcription.

We also immunostained for H3K9ac and H3K4me3 (Supplemental Fig.  1), as markers for active transcription.