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Overall, we processed 131 primary specimens through the course of this study; however, most of the tumors were too small for the marker expression profiling.
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Eighteen percent of type I neuroblasts mis-expressing btd lost Ase expression and generated progeny displaying a marker expression profile that is typically diagnostic of an immature INP or an INP.
Similarly, hCNS-SC can be expanded either as neurospheres or in extended adherent monolayer with a morphology and marker expression profile consistent with radial glia NS cells.
To shed light on the characteristics of human dermal MSCs, this study was designed to identify and isolate dermal MSCs by a specific marker expression profile, and subsequently rate their mesenchymal differentiation potential.
A comparison of the harvested BMSCs from manual and automated cultures using clinically acceptable protocols showed no differences in cell yields, viabilities, surface marker expression profiles, and in vivo osteogenic abilities.
We characterized putative germ cell precursors, demonstrating their close resemblance to PGCs based on (1) morphology and (2) marker expression profiles at the mRNA and protein levels.
Primary invading cells consisted in an homogeneous population of SSC lo) CD11b hi) macrophages (fig. S3B and [33]) that exhibited a F4/80(lo)Ly-6C(hi) membrane marker expression profile.
Cells at this stage of differentiation were chosen for transduction based on their marker expression profile, which indicated a possible commitment to the germ lineage.
In any case, our results indicate that committed ObL cells unambiguously defined by marker expression profile and functional endpoints exhibit diverse molecular phenotypes as characterized by expression of non-osteoblastic mesenchymal lineage markers.
We conclude that ΔN89β-catenin signaling cells within tumors show marker expression profiles that mirror those of CFC alveolar progenitors from normal gland and are bipotent, giving rise to luminal and basal cell types in vitro.
A Kruskal-Wallis test was used for the initial comparisons of the distribution of cell surface marker expression profiles of nCD4+, aCD4+, and aCD4− NKT cell subsets, followed by pair-wise comparison tests.
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