Compared to primary tumor material, a higher percentage of lung metastases showed expression of the analyzed markers (examples are shown in Fig. 1, right colums).
In that situation, additional independent markers (for example inflammatory markers, possibly genetic markers) will still be needed if we are to attain a more complete prediction of the outcomes in individual EPA patients.
Typically, ~300 virgin females bearing a second chromosome balancer with a dominant marker, for example CyO, are collected.
A pre-operative marker, for example, could significantly help in determining the most appropriate treatment for a particular patient [ 7].
Another way of dealing with challenges was to set a time marker (for example, end of year) and then re-assess the situation.
To improve the sensitivity of the detection of micrometastases, immunohistochemistry (IHC) for a particular marker, for example pan-cytokeratin in breast cancer patients, has been employed [ 12].
A number of multivariate models were then constructed, with potential explanatory variables grouped according to category of risk marker (for example, classic risk factors, markers of insulin resistance, inflammatory markers, markers of haemostasis) and adjusted for in the analyses.
Get a permanent marker, for example, a Sharpie.
The second design makes use of surrogate markers (for example, a protein, metabolic, epigenetic, or other marker), especially validated markers, to conduct trials with a smaller sample size and a shorter follow-up period than traditional trials require.
Moreover, the Nei minimum distance [ 25] could be inappropriate when working with various markers, for example when mixing data obtained with markers with different heterozygosis levels (e.g. mixing microsatellite and SNP data).
