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In addition, macrophages were larger, more vacuolated and displayed different surface marker distribution compared with resident and mBSA-elicited macrophages (Cook et al., 2003).
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An N-terminal GFP-CLN3 construct was expressed in HEK293 cells and its distribution compared with various markers of cellular compartments and with that of the human CLN3.
We defined the lower and upper bound thresholds of significance, by analyzing the marker distribution, by comparing (in a chi-test) the observed distribution of the number of markers per bandwidth with that expected under a Poisson distribution.
The two PDW233 × Bhalegaon 4 [ 36] and Latino × Primadur maps [ 35], for which the original segregation data were not available, were inspected for their homogeneity in marker distribution and inter-marker distances as compared to the component maps before to integrate their map information data into the consensus map.
A Kolmogorov-Smirnov test for two populations was implemented to compare the observed marker distribution frequencies with expected distribution frequencies under the assumption of randomness.
dicoccoides G18-16 was much less affected by uneven marker density distribution as compared to the intra-specific T. durum maps.
Some fluctuations in the marker distribution were observed, especially in the COX1 locus, which presented a lower density compared to the rest of the genome.
However, marker distribution can become ill-conditioned when marker placement is symmetrical with respect to the mean of the markers.
Similarly, the distributions of DArT markers derived from subtracted vs. un-subtracted libraries exhibited expected shifts in marker distribution.
The distributions of DArT markers derived from sample-specific vs. pooled metagenomes exhibited expected shifts in marker distribution.
Remarkably, the knock-down of PHB induced strong changes in the intracellular distribution of these markers, as compared to control (mock) cells).
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