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Molecular marker determination, however, is technically demanding and requires reproducible and validated test procedures.
Tumor marker determination is a simple, inexpensive test, available in most centers where lung cancer is diagnosed.
Thus, individual patient data were available from five centres, independent for study design, patient recruitment, and blood marker determination.
Importantly, many reports have shown that serum, rather than heparinized plasma, should be used for cardiac marker determination [ 10, 11].
The high throughput SNP marker determination can be carried out at relatively low cost and is less laborious than other methods used.
All five patients have had regular follow-up consultations with a three-monthly ultrasound and tumour marker determination, and have no evidence of progression in the testis at a median follow-up of 18 months.
Similar(51)
GFAP levels were quantified in the frontal and parietal cortex of the same four cohorts of animals used for the neuronal marker determinations described in the previous section (Figure 6D, ANOVA p = 0.05 and ANOVA p = 0.0062, respectively).
Post-treatment surveillance of these patients consisted in serum tumour marker determinations and imaging studies.
All marker determinations were carried out by a single experienced researcher (RG) who was blinded to all information regarding the sample and UKCTOCS volunteer.
Particular attention should be paid to patients with radiological stage I disease and elevated tumor markers: patients should be monitored with frequent post-orchiectomy serum marker determinations until complete marker normalization before these patients are classified as having true stage I disease.
Serum was kept at −80 °C until the moment of markers determination.
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