Aside from the above-described modules overlapping with the UK-Biobank array, we expanded modules dedicated to non- HLA MHC region markers, deep coverage of known and predicted LoF variants, and untranslated regions (UTR -specific modUTR -specific
With increasing use of next generation sequencing technology that can combine multiple markers, deep-level biodiversity studies will be more able to demonstrate true estimates of protist diversity and may provide useful information for the cultivation of a greater proportion of presently unculturable species.
The presence of ovarian endometriomas has been reported as being a marker for deep endometriosis [16] and multifocal deep vaginal, intestinal and ureteric lesions [5].
In NREM sleep, several large amplitude ERP components are thought to reflect inhibition of information processing and may reflect the brain's capacity to generate delta frequency EEG activity, a marker of deep slow wave sleep [1].
In these experiments, NIH/3T3 cells were transfected with wt Akt1-GFP or the respective mutants that lack one of the phosphorylation sites, Akt1 T308A-GFP Akt1Akt1 S473A-GFP, and further stained with a specific mitochondrial marker, MitoTracker Deep Red, and analyzed by confocal microscopy.
The mitochondrial marker showed deep divergence between reciprocally monophyletic clades representing distinct ecodomains within the Neotropics.
The lack of synapomorphic gene arrangements among copepods has cast doubt on the utility of gene order as a useful molecular marker for deep phylogenetic analysis.
In many animals, it is present in low copy number and highly conserved, which has led to its use as a marker for deep phylogenetic relationships [ 16].
The lack of synapomorphic gene arrangements among copepods raises questions concerning the use of gene order as a useful molecular marker for deep phylogenetic analysis.
Our analysis corroborates results by previous authors [ 60] suggesting that attractin represents an effective phylogenetic marker, recovering deep metazoan relationships and important clades such as Bilateria, its split into Deuterostomia and Protostomia, and the subdivision of the latter in Ecdysozoa and Spiralia (Lophotrochozoa).
