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The marker could help improve cancer diagnosis, the researchers say.
With approximately two-thirds of metastatic colorectal cancer patients being wild-type KRAS, this marker could help better use EGFR therapy and spare patients from inappropriate treatment.
The findings of the present study suggest that this marker could help select patients who are unable to benefit from chemotherapy, such as those with HER2-negative and hormone receptor-positive tumors with low proliferation.
In addition, as about 30% of early-stage NSCLC relapse (El-Sherif et al, 2006), a prognostic marker could help stratify patients who might benefit from a more aggressive treatment.
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Therefore, the identification of additional reliable markers could help to tailor radiation regimens in order to administer the optimal therapeutic dose while minimizing toxicity.
Such markers could help physicians to identify patients at high risk for specific complications, thereby allowing a personalized approach to monitoring and preventing progression to costly co-morbidities.
These markers could help to predict at diagnosis the treatment response of patients with cHL and then to propose new targeted therapies to refractory patients.
However, some markers could help to resolve part of them.
Ultimately these biomarkers or patterns of markers could help to improve animal selection programs.
In addition, preoperative diagnostic markers could help to evaluate the chemosensitivity of the cancer.
Suitable molecular markers could help to refine individual risk stratification and treatment plans [ 30].
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